Toxicology Assessment of Matador in Heart Histology and Lipid Profile on edible fish Cyprinus Carpio

Aquatic ecosystems are continuously exposed to environmental pollutants due to rapid agricultural and industrial development; among these, pesticides are a major threat to water contamination and affect non-target aquatic organisms. The present study examined the acute toxicity of the pyrethroid pesticide Matador on the freshwater fish Cyprinus carpio. Sub-lethal concentrations of Matador were calculated for the freshwater fish Cyprinus carpio, which were 0.0018 ml/L after 24, 48, 72 and 96 hours. The calculated 1/10th sub-lethal concentration of matador was induced in different aquariums for the treated group against the control group for the evaluation of heart lipid panel, serum SGOT and observed alterations in fish heart histology at the intervals of 7, 14, 21 and 28 days. The treated group exhibited abnormal swimming, reduced feeding, bottom swimming, as well as erratic swimming behaviour. Heart lipid panel cholesterol, TGS, LDL, VLDL and the enzyme SGOT of fish showed highly significant elevation (p<0.001), but HDL showed a highly significant decline(p<0.01). Histology of the heart revealed reduced compactness of cardiac muscle fibre, poor visibility of intercalated discs and nuclear damage in the acute study. Matador induced, caused an adverse effects on the fish's health, a hazardous impact on water bodies, non-target animals and human health.